Reference number
ISO 23921:2020
ISO 23921:2020
© ISO 2025
International Standard
ISO 23921:2020
Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke with an intense smoking regime — Method using LC-MS/MS
Edition 1
2020-09
2020-09
Abstract
This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of cigarette mainstream smoke with the intense smoking regime specified in ISO 20778 by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
General information
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Status: PublishedPublication date: 2020-09Stage: International Standard published [60.60]
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Edition: 1Number of pages: 14
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Technical Committee :ISO/TC 126ICS :65.160
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